Boronic acid is a Part of organic chemistry. Its use for making more bio-medical products.
Boronic acid-containing polymers with their unique reactivity and stimuli-responsive behavior have potential applications as self-healing materials, therapeutic agents, self-regulated drug delivery systems, nucleotide adsorbents, and sensors for sugars and glycoproteins.
Boronic acids contain trivalent boron atoms bonded to one alkyl/aryl substituent and two hydroxyl groups (R–B(OH)2). Some Boronic acid’s characteristics are suitable for Biomedical application,including the treatment of HIV, obesity, diabetes, and cancer. Functionalization with boronic acid (co)polymers has proven to be a convenient method to render surfaces useful for cell culturing. For example, Saito and coworkers demonstrated that surfaces functionalized with a terpolymer (PMBV) of 2-methacryloyloxyethyl phosphorylcholine, butyl methacrylate, and 4-vinylphenylboronic acid promoted the adsorption of the glycoprotein fibronectin by boronate ester formation.
The product of a third oxidation of borones, boric acid, is a very stable and a relatively benign compound to humans. Their unique properties as mild organic Lewis acids and their mitigated reactivity profile, coupled with their stability and ease of handling, makes boronic acids a particularly attractive class of synthetic intermediates.
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